Three African countries conducted randomized controlled trials that showed statistically significant evidence in favor of circumcision against HIV transmission. One study led by the University of Illinois involved 2,784 men between the ages of 18 and 24. The trial was stopped prematurely after it revealed that circumcision had prevented 53% HIV transmission in the circumcision group. The ANRS sponsored another trial that involved 3,273 men ages 16-24. The interim results showed that circumcision led to 60% fewer infections in men.
Heterosexual men who circumcise their male partners are less likely to contract HIV.
A review of research shows that male circumcision can reduce the risk of HIV infection among heterosexual men. It is also associated with decreased rates of other sexually transmitted diseases, which can increase the risk of HIV in women and children. Also, circumcision results in lower HIV transmission rates to their female partners by men who have undergone it. It is not known why circumcision decreases HIV infection risk in men.
Three landmark phase III clinical trials in Africa proved that circumcision can reduce the risk of HIV infecting heterosexual men by up to 60%. These findings were consistent with earlier ecological and observational studies. In 2010, the World Health Organization recommended male circumcision as part of a comprehensive HIV prevention package. While a low prevalence of male circumcision may be associated with lower HIV infection rates than other groups, the benefits of circumcision seem to be greatest in those who have had documented exposure to HIV-infected women partners.
It reduces the risk of transmission from female to male
Studies have shown that male circumcision can reduce the risk of HIV transmission between males and females by 60%. The Kaiser Daily HIV/AIDS Report published the study’s results in November 2005. The benefits of circumcision not only have a sexual benefit, but they also have a social responsibility. The chances of having sexual encounters with prostitutes are lower for men who have undergone circumcision. They may have fewer sexual encounters, which reduces the risk that HIV will be transmitted.
It protects MSM contre herpes simplex virus
According to Tabet SR’s studies, it protects MSM from HIV infection and herpes-simplex virus. HIV-infected women and men were equally at risk, but some showed a lower risk of getting infected. Amsterdam’s study examined the relationship between HIV risk, herpes infection, and HIV risk. The results of this study have been published in J Infect Dis.
The research included 1847 MSM who had been to the doctor at least twice between 1984 and 2003. 1207 people tested positive for HSV-1 antibodies and 759 for HSV-2. Of these men, 30% tested positive for both HSV-1 and HSV-2 antibodies. The participants were primarily Dutch nationals and averaged 29 years old. The authors concluded that vaccination against the herpes simplex virus was safe and effective in preventing outbreaks.
Another study found that MSM with high levels of sexual activity were more susceptible to the virus. Men with high sexual activity were more likely than women with fewer contacts to contract the virus. Further, MSM with higher sexual activity were more likely to contract HSV-1. Combining antiviral therapy with suppressive therapy can reduce the risk by 70% to 80%. This combination of education, prevention, and education could be an effective way to stop the HIV epidemic among MSM.
It is cost-effective
Researchers highlight the cost-effectiveness and cost-effectiveness for adult male circumcision in a PLOS collection, Voluntary Medical Male Circumcision, and HIV Prevention: Preliminary Results. The project aims to circumcise at least 20.3 million boys and men in 14 priority countries. The researchers estimate that circumcising these men could prevent 3.4 million new cases of HIV and save 16 billion dollars in medical costs over 15 years.
While circumcision is known to reduce HIV infection among men, the cost-effectiveness of the procedure compared to other approaches is still unclear. Using a cost-effectiveness model, Kahn and colleagues incorporated data from a randomized control trial in Gauteng Province, South Africa. They found that male circumcision could reduce the rate of new HIV infection acquisition by 60 percent. This intervention is more effective than traditional methods of reducing the spread.